They tear their hair out in frustration together in "A Shot in the Dark" when Peter's stupid idea causes Lois to start beating him.Stewie enjoys taunting Meg about several topics of her supposed "ugliness", her virginity, and inability to keep a boyfriend, but she rarely seems to notice his comments, where all the main cast except Brian are not able to hear or interpret Stewie's speech unless at writer's discretion.
Lois also makes a point of washing Stewie's diapers with Meg's clothes and get a sarcastic attitude when Meg asks for advice on asking out Kent Lastname in "Friends Without Benefits".
Lois does show a slightly kinder side in "Call Girl" when she refers to Meg by her real name while dismissing Chris and Stewie as "dummy and big-head." Peter is usually the one who bears a great animosity towards her: berating her, hitting her while once on steroids in "The Father, the Son, and the Holy Fonz", even shooting her in "Peter's Daughter".
Meg explains in "A Fistful of Meg" that her father changed her birth certificate to "Megatron" after her mother had already selected Megan.
Despite this, she is still commonly called Megan such as by Mr. When Family Guy debuted in 1999, her age is assumed to be fifteen years old although this is never established.
Even though he gets into arguments with her from time to time, Chris usually goes to Meg for advice.