These hills are part of the Appalachian Ridge-and-Valley Province, which is characterized by fertile river valleys flanked by narrow, elongate ridges.
Greeneville is located roughly halfway between Bays Mountain to the northwest and the Bald Mountains— part of the main Appalachian crest— to the southeast. Route 11E (Andrew Johnson Highway), which connects Greeneville with Morristown to the west, intersects U. 321 in Greeneville and the merged highway proceeds northeast to Johnson City.
Healthcare services are enhanced by Greeneville's close proximity to major medical centers in Knoxville and the Tri-Cities area.
Greeneville offers a variety of transportation for your needs.
The valley in which Greeneville is situated is part of the watershed of the Nolichucky River, which passes a few miles south of the town. Route 321 follows Main Street through the center of the town and connects Greeneville to Newport to the southwest. Tennessee State Route 107, which also follows Main Street and Andrew Johnson Hwy, Greeneville to Erwin to the east and to the Del Rio area to the south. D.) village existed at the Nolichucky's confluence with Big Limestone Creek (now part of Davy Crockett Birthplace State Park).