Up to 10 masked attackers dressed in military uniforms stopped a convoy in Egypt province, 140 miles south of Cairo, as the group was heading towards Saint Samuel the Confessor Monastery in Maghagha to pray.
The gunmen, who arrived in three four-wheel drive vehicles, used automatic weapons to spray bullets at the convoy before fleeing.
Egyptian forces have struck bases in which militants who waged a deadly attack against Christians have been trained.
President Abdel-Fattah el-Sissi said fighter jets struck militant bases in eastern Libya in retaliation for an attack by suspected Islamic State militants that killed 28 Christians and wounded another 22 south of Cairo.
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